What is the mechanism of action of antipyretic analgesics
There are many kinds of antipyretic, analgesic and anti-inflammatory drugs, but they all have antipyretic, analgesic, anti-inflammatory and anti rheumatic effects, and their mechanisms of action are very similar.
The mechanism of antipyretic and analgesic drugs is to inhibit the biosynthesis of prostaglandins in the body. Prostaglandins widely exist in various important tissues and body fluids of human and mammals. Many cells can synthesize prostaglandins.
Arachidonic acid can be released from phospholipids in two ways. One is the catalysis of prostaglandin synthetase in cell particles to produce various substances, which participate in the regulation of a variety of physiological and pathological processes, such as inflammation, fever, pain, coagulation, gastric acid secretion and the development of blood vessels, bronchus and smooth muscle Relax and contract.
Another way is to participate in the regulation of vascular strength, some physiological reactions, various damage factors, and also induce the synthesis of a variety of cytokines. These factors can induce phosphatase, increase the synthesis of preaglandular hormone, and participate in the body's inflammatory reaction and other pathological processes.
The mechanism of antipyretic and analgesic drugs is to inhibit the biosynthesis of prostaglandins in the body. Prostaglandins widely exist in various important tissues and body fluids of human and mammals. Many cells can synthesize prostaglandins.
Arachidonic acid can be released from phospholipids in two ways. One is the catalysis of prostaglandin synthetase in cell particles to produce various substances, which participate in the regulation of a variety of physiological and pathological processes, such as inflammation, fever, pain, coagulation, gastric acid secretion and the development of blood vessels, bronchus and smooth muscle Relax and contract.
Another way is to participate in the regulation of vascular strength, some physiological reactions, various damage factors, and also induce the synthesis of a variety of cytokines. These factors can induce phosphatase, increase the synthesis of preaglandular hormone, and participate in the body's inflammatory reaction and other pathological processes.